Patent · US Active

Compounds for inhibiting KSP kinesin activity

US8796460B2 · kind B2 · utility

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37Claims
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Assignee

Inventors

Key dates

Filing dateOct 16, 2008
Grant dateAug 5, 2014
Priority date
Expiry dateJul 9, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D515/20
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds of Formula (I), below, (wherein X, R1, R2, R3, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity. Formula I

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.