Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue of bone

US8802122B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Helen H. Lu · New York, US
• Jeffrey Spalazzi · Staten Island, US
• Kathie Dionisio · Andover, US

Key dates

• Filing date: Dec 22, 2009
• Grant date: Aug 12, 2014
• Expiry date: Aug 24, 2032

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2430/34
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.