Activated collagen scaffold materials and their special fused active restoration factors
US8802396B2 · kind B2 · utility
1Cited by
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15Claims
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Key dates
| Filing date | Dec 1, 2006 |
| Grant date | Aug 12, 2014 |
| Priority date | — |
| Expiry date | Jun 7, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/21
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are activated collagen scaffold materials as well as their special fused active restoration factors useful for promoting tissue repair, such as bone damage repair or nerve injury repair. The special fused active restoration factors are fusion proteins comprising a collagen-binding domain (CBD) at N-/C-terminus of cytokines, wherein the collagen-binding domain is a polypeptide consisting of 7-27 amino acid residues with a conservative sequence shown in SEQ ID NO:1 at N-terminus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.