Patent · US Active

C-28 amides of modified C-3 betulinic acid derivatives as HIV maturation inhibitors

US8802661B2 · kind B2 · utility

6Cited by

4References

22Claims

0Family size

Assignee

Bristol-Myers Squibb Company · US

Inventors

Alicia Regueiro-Ren · Wallingford, US
Zheng Liu · Beacon Falls, US
Jacob Swidorski · Wallingford, US
Nicholas A. Meanwell · East Hampton, US
Sing-Yuen Sit · Meriden, US
Jie Chen · Houston, US
Yan Chen · Foster City, US
Ny Sin · East Hampton, US

Key dates

Filing date	Jun 2, 2011
Grant date	Aug 12, 2014
Priority date	—
Expiry date	Mar 12, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P37/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, modified C-3 and C-28 betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.