Adenine derivatives
US8802684B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 20, 2013 |
| Grant date | Aug 12, 2014 |
| Priority date | — |
| Expiry date | Sep 20, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (I):wherein R1 is C1-6alkylamino, or C1-6alkoxy; R2 is a group having the structure:n is an integer having a value of 1 to 6; Het is a 6-membered saturated heterocycle containing one nitrogen atom wherein Het is attached to the —(CH2)n— moiety at any carbon atom of the heterocycle; R3 is hydrogen, C1-8alkyl, or C3-7cycloalkylC0-6alkyl; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.