Production of peptides and proteins by accumulation in plant endoplasmic reticulum-derived protein bodies
US8802825B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 17, 2009 |
| Grant date | Aug 12, 2014 |
| Priority date | — |
| Expiry date | Nov 16, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/8257
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A nucleic acid molecule is disclosed as containing a first nucleic acid sequence comprising a nucleotide sequence that encodes a γ-zein protein, or a fragment thereof, that is capable of directing and retaining a protein towards the endoplasmic reticulum (ER) of a plant cell and a nucleic acid sequence encoding a peptide or protein of interest. Methods of using this nucleic acid molecule for transforming host plant cells in order to improve the production and purification of the peptide or protein of interest are also disclosed. Polypeptides encoded by the nucleic acids and produced the methods are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.