Amide derivatives of benzene-sulfonanilide, pharmaceutical composition thereof and method for cancer treatment using the same
US8802895B2 · kind B2 · utility
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2References
27Claims
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Key dates
| Filing date | Oct 18, 2010 |
| Grant date | Aug 12, 2014 |
| Priority date | — |
| Expiry date | Apr 7, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides a compound of formula (I), a pharmaceutical composition thereof, a method of preparing a medicament for the treatment of a cancer, and a method of treating cancers. The invention exhibits merits against cancers such as significantly higher potency and effectiveness over a broader range of cancers. In formula (I), Ra is a benzyl group with alkyl and/or alkoxy; Rb is selected from H and alkyl groups; Rf is an alkyl; and R3 is selected from a substituted phenyl, a heterocyclic group, andwherein Rc is selected from a fused ring, fused rings, and any bivalent cyclic group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.