Patent · US Active

Genetically modified bacterium of the species Listeria monocytogenes

US8808683B2 · kind B2 · utility

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16Claims

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Assignee

Merck Patent GmbH · DE

Inventors

Peter Rossmanith · Baden, AT
Karin Fruehwirth · Ternitz, AT
Martin Wagner · Madison, US
Sabine Fuchs · Laa an der Thaya, AT

Key dates

Filing date	Apr 29, 2011
Grant date	Aug 19, 2014
Priority date	—
Expiry date	Apr 29, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/166
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to a genetically modified bacterium of the species Listeria monocytogenes, wherein the genomic locus of the transcriptional factor PrfA has been deleted, characterized in that it comprises on genomic level an artificial sequence that acts as internal amplification control, the use of this bacterium as well as a method for detecting and determining qualitatively and/or quantitatively the occurrence of wild type Listeria monocytogenes in a sample suspected to be contaminated with said micro-organism and a kit.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.