Patent · US Active

Stabilized open form transglutaminase as a diagnostic indictor for autoimmune diseases

US8808980B2 · kind B2 · utility

0Cited by

0References

5Claims

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Assignee

Zedira GmbH · DE

Inventors

Martin Hils · Darmstadt, DE
Ralf Pasternack · Griesheim, DE
Johannes Weber · Stuttgart, DE

Key dates

Filing date	Nov 11, 2010
Grant date	Aug 19, 2014
Priority date	—
Expiry date	Nov 11, 2030

Classification

Technology area (CPC G)Physics
CPC primaryG01N2333/91085
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to the diagnosis of disorders or dysfunctions characterized by autoimmune responses to the enzyme class of transglutaminases. The present invention provides a novel open structure of the transglutaminases in a stabilized form which renders new epitopes accessible for antibody-binding.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.