IRES mediated multicistronic vectors
US8809017B2 · kind B2 · utility
3Cited by
1References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 24, 2012 |
| Grant date | Aug 19, 2014 |
| Priority date | — |
| Expiry date | May 24, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/206
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to nucleic acid molecules comprising at least one nucleic acid sequence encoding for a peptide or protein of interest, at least one nucleic acid sequence encoding for a selectable marker, and at least one IRES sequence, wherein the at least one IRES sequence is located between the at least one nucleic acid sequence encoding for the peptide or protein of interest and the at least one nucleic acid sequence encoding for the selectable marker. Furthermore, this invention relates to host cells comprising such nucleic acid molecule and to methods of recombinant protein expression using such host cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.