Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation
US8809303B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Apr 9, 2009 |
| Grant date | Aug 19, 2014 |
| Priority date | — |
| Expiry date | Apr 9, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are described for reducing cytoskeletal rearrangement and intercellular gap formation by contacting cells with an aminoalkyl glucosaminide phosphate. In particular, the methods can be used to reduce actin cytoskeletal rearrangement and/or intracellular gap formation related to ischemic or ischemia-reperfusion events and to alleviate diseases or conditions related to increased actin cytoskeletal rearrangement.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.