Sulfonamides as inhibitors of Bcl-2 family proteins for the treatments of cancer
US8809352B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 8, 2010 |
| Grant date | Aug 19, 2014 |
| Priority date | — |
| Expiry date | Sep 8, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention includes novel compound and methods of treating a disease or disorder by antagonizing Bcl-2 family proteins, particularly compounds of formula (I):or pharmaceutically acceptable salt thereof, as well as methods of treating a disease, disorder, or syndrome associated with Bcl-2 inhibition, particularly hyperproliferative diseases. The present invention also includes pharmaceutical compositions including compounds of formula I and pharmaceutically acceptable salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.