Pepstatin A derivatives

US8809498B2 · kind B2 · utility

Assignee

• Freie Universitaet Berlin · DE

Inventors

• Claudia Borelli · Munich, DE
• Hans Christian Korting · Berlin, DE
• Elisabeth Ruge · Bad Endorf, DE
• Hans Dieter Hoeltje · Berlin, DE
• Robert Huber · Midland, US
• Beate Koksch · Berlin, DE
• Cosimo Damiano Cadicamo · Berlin, DE

Key dates

• Filing date: Apr 30, 2009
• Grant date: Aug 19, 2014
• Expiry date: Feb 15, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K7/02
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a compound having a structure according to the general formula P3-P2-P1-P1′-P2′ (I), wherein residues P3, P2, P1, P1′ and P2′ are specifically defined and may be, e.g., certain amino acid residues. The invention further relates to the use of said compound and to a method for synthesizing a peptide.