Tripartite oligonucleotide complexes and methods for gene silencing by RNA interference
US8809514B2 · kind B2 · utility
10Cited by
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25Claims
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Key dates
| Filing date | Sep 20, 2007 |
| Grant date | Aug 19, 2014 |
| Priority date | — |
| Expiry date | May 1, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2330/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are tripartite oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene. The tripartite oligonucleotide complexes of the disclosure may include a conjugate moiety that facilitates delivery to a cell, tissue or organism without the aid of a transfection reagent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.