Patent · US Active

Single molecule optical spectroscopy in solid-state nanopores in a transmission-based approach

US8810787B2 · kind B2 · utility

4Cited by

4References

23Claims

0Family size

Assignees

IMEC · BE
Katholieke Universiteit Leuven, KU LEUVEN R&D · BE

Inventors

Pol Van Dorpe · Spalbeek, BE
Iwijn De Vlaminck · Stanford, US
Liesbet Lagae · Leuven, BE
Gustaaf Borghs · Kessel-Lo, BE

Key dates

Filing date	Dec 9, 2009
Grant date	Aug 19, 2014
Priority date	—
Expiry date	Dec 9, 2029

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S977/924
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Methods and apparatus in the field of single molecule sensing are described, e.g. for molecular analysis of analytes such as molecular analytes, e.g. nucleic acids, proteins, polypeptides, peptides, lipids and polysaccharides. Molecular spectroscopy on a molecule translocating through a solid-state nanopore is described. Optical spectroscopic signals are enhanced by plasmonic field-confinement and antenna effects and probed in transmission by plasmon-enabled transmission of light through an optical channel that overlaps with the physical channel.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.