Proton decoupled hyperpolarized magnetic resonance imaging
US8812076B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Nov 21, 2006 |
| Grant date | Aug 19, 2014 |
| Priority date | — |
| Expiry date | Nov 3, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/485
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A system and method for improving available signal-to-noise ratio (SNR) and speed of MR imaging of hyperpolarized substances is disclosed. The system and method include decoupling spin effects of hydrogen nuclei from non-hydrogen nuclei of interest during sampling of MR signals therefrom. Though the hydrogen nuclei of the hyperpolarized substance may not be directly bonded to the non-hydrogen nuclei of interest, resonance splitting may still impact SNR. Long range decoupling improves T2* time, and thus preserves signal strength and available SNR.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.