Aglycosylated immunoglobulin mutants
US8815237B2 · kind B2 · utility
9Cited by
1References
19Claims
0Family size
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Key dates
| Filing date | Dec 5, 2008 |
| Grant date | Aug 26, 2014 |
| Priority date | — |
| Expiry date | Sep 26, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/41
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is based, in part, on our discovery of immunoglobulins (e.g., immunoglobulin G (IgG)) polypeptides (e.g., murine or human IgG, such as human IgG1) that are aglycosylated yet retain the ability to bind to an Fc receptor, such as an activating Fc receptor (e.g., FcγRIIA and/or FcγRIIIA).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.