Method for obtaining a natural mixture of conjugated equine estrogens depleted in non-conjugated lipophilic compounds

US8815299B2 · kind B2 · utility

Assignee

• ABBOTT PRODUCTS GMBH · DE

Inventors

• Ivan Ban · Hannover, DE
• Klaus-Guenter Gerling · Laatzen, DE
• Hans-Joerg Mueller · Hannover, DE
• Stefan Wachsmann · Hannover, DE

Key dates

• Filing date: Jun 13, 2008
• Grant date: Aug 26, 2014
• Expiry date: Jan 20, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/56
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for obtaining an extract containing the natural mixture of conjugated equine estrogens by liquid-liquid extraction of the mixture of conjugated equine estrogens, wherein the mixture obtained is depleted in non-conjugated lipophilic compounds selected from the group consisting of non-conjugated flavonoids, non-conjugated isoflavonoids, non-conjugated norisoprenoids, non-conjugated steroids, in particular androstane and pregnane steroids, and comparable non-conjugated compounds.