Method and materials for the cooperative hybridization of oligonucleotides
US8815507B2 · kind B2 · utility
2Cited by
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Key dates
| Filing date | Mar 18, 2011 |
| Grant date | Aug 26, 2014 |
| Priority date | — |
| Expiry date | Aug 20, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/50
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A two-stranded intermediary complex and cooperative hybridization method are provided. The complex has been designed so that target oligonucleotides of independent sequence can cooperatively and simultaneously hybridize to it. The cooperative hybridization mechanism is robust and modular, smoothly integrating with other dynamic DNA components to form cascaded reaction networks that can perform a variety of functions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.