Patent · US Active

Biosynthetic pathway for heterologous expression of a nonribosomal peptide synthetase drug and analogs

US8815562B2 · kind B2 · utility

5Cited by

4References

18Claims

0Family size

Assignees

THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US
Allegheny Singer Research Institute · US
COLORADO STATE UNIVERSITY RESEARCH FOUNDATION · US

Inventors

David H. Sherman · Ann Arbor, US
Garth David Ehrlich · Pittsburgh, US
Benjamin Janto · Pittsburgh, US
Robert M. Williams · Chesterfield, US
Christopher M. Rath · San Diego, US

Key dates

Filing date	Apr 15, 2011
Grant date	Aug 26, 2014
Priority date	—
Expiry date	Apr 27, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P17/182
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention also discloses polynucleotide sequences useful for heterologous expression in a convenient microbial host for the synthesis of the NRPS derived drug.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.