Transcription biomarkers of biological responses and methods
US8815779B2 · kind B2 · utility
1Cited by
62References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 16, 2009 |
| Grant date | Aug 26, 2014 |
| Priority date | — |
| Expiry date | Sep 16, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention provides transcription regulatory control sequences, the activity of which function as biomarkers for a variety of biological responses. This invention also provides expression constructs in which a biomarker transcription regulatory sequence is operably linked with a sequence for a reporter. Cells that comprise these expression constructs can be used in assays to identify conditions that modulate activity of the biological response.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.