3′-azido purine nucleotide prodrugs for treatment of viral infections
US8815829B2 · kind B2 · utility
22Cited by
2References
14Claims
0Family size
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Key dates
| Filing date | Dec 9, 2009 |
| Grant date | Aug 26, 2014 |
| Priority date | — |
| Expiry date | Apr 22, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/207
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds, compositions and methods for treating or preventing viral infections, in particular, HIV, and HBV, in human patients or other animal hosts. The compounds are 3′-azido-2′,3′-dideoxy purine monophosphates, and pharmaceutically acceptable, salts, prodrugs, and other derivatives thereof. In particular, the compounds show potent antiviral activity against HIV-1 and HBV.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.