Treatment of Acinetobacter with alginate oligomers and antibiotics

US8815831B2 · kind B2 · utility

Assignee

• AlgiPharma AS · NO

Inventors

• Edvar Onsoyen · Svelvik, NO
• Rolf Myrvold · Sandvika, NO
• Arne Dessen · Røyken, NO
• David Thomas · North York, CA
• Timothy Rutland Walsh · Cardiff, GB

Key dates

• Filing date: Jun 3, 2010
• Grant date: Aug 26, 2014
• Expiry date: Jun 3, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P41/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides a method to improve the efficacy of an antibiotic to inhibit the growth of Acinetobacter, said method comprising using said antibiotic together with an alginate oligomer. The Acinetobacter may be on an animate or inanimate surface and both medical and non-medical uses and methods are provided. In one aspect the invention provides an alginate oligomer for use together with at least one antibiotic in treating a subject infected, suspected to be infected, or at risk of infection, with Acinetobacter. In another aspect the method can be used to combat Acinetobacter contamination of a site e.g., for disinfection and cleaning purposes.