Mitochondrial activity inhibitors of cancer-initiating cells and use thereof
US8815844B2 · kind B2 · utility
2Cited by
0References
3Claims
0Family size
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Key dates
| Filing date | May 20, 2010 |
| Grant date | Aug 26, 2014 |
| Priority date | — |
| Expiry date | Jul 15, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the compounds useful in the prevention and/or treatment of tumors. More specifically the present invention relates to inhibitors of the activity of the electron transport chains and/or the mitochondrial TCA cycle in glioma-initiating cells (GICs) for use in a method for preventing and/or treating tumors presenting glioma-initiating cells (GICs) in a subject who has undergone a prior removal of a tumor glioma bulk. The present invention further provides a pharmaceutical composition containing the inhibitors of the invention and a screening method for identifying the inhibitors of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.