Substituted pyrazin-2-ones and substituted 5,6,7,8-tetrahydroquinoxalin-2-ones and methods of use thereof

US8815859B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Gerard Botton · Buc, FR
• Eric Valeur · Brétigny-sur-Orge, FR
• Christine Charon · Gometz-le-Châtel, FR
• Micheline Kergoat · Les Ulis, FR
• Samer Elbawab · Les Ulis, FR

Key dates

• Filing date: Mar 31, 2009
• Grant date: Aug 26, 2014
• Expiry date: Jul 10, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Arylpyrazinone derivatives of formula (I),as insulin secretion stimulators, the preparation and use of these pyrazinone derivatives for the prophylaxis and/or treatment of diabetes and pathologies associated.