Diaminocyclohexane compounds and uses thereof

US8815909B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• William R. Ewing · Yardley, US
• Yeheng Zhu · Stockton, US
• Chongqing Sun · Plainsboro, US
• Yanting Huang · Pennington, US
• Maheswaran Sivasamban Karatholuvhu · Chennai, IN
• Scott A. Bolton · Newtown, US
• Laxman Pasunoori · Warangal, IN
• Sunil Kumar Mandal · Bengaluru, IN
• Philip M. Sher · Plainsboro, US

Key dates

• Filing date: Jul 16, 2012
• Grant date: Aug 26, 2014
• Expiry date: Jul 29, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides compounds of Formula (I):or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators of the NPY Y4 receptor and may be used for the treatment and prophylaxis of various diseases and conditions.