Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 28, 2005 |
| Grant date | Aug 26, 2014 |
| Priority date | — |
| Expiry date | Apr 22, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K33/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to pharmaceutical formulations comprising at least one acid-labile proton pump inhibiting agent and at least one antacid, which have improved bioavailability, chemical stability, physical stability, dissolution profiles, disintegration times, safety, as well as other improved pharmacokinetic, pharmacodynamic, chemical and/or physical properties. The present invention is directed to methods, kits, combinations, and compositions for treating, preventing or reducing the risk of developing a gastrointestinal disorder or disease, or the symptoms associated with, or related to, a gastrointestinal disorder or disease in a subject in need thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.