Heterocyclic carbonyl compounds

US8815924B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Dieter Dorsch · Ober-Ramstadt, DE
• Rolf Gericke · Seeheim-Jugenheim, DE
• Werner Mederski · Zwingenberg, DE
• Norbert Beier · Reinheim, DE
• Florian Lang · Gilching, DE

Key dates

• Filing date: Apr 4, 2005
• Grant date: Aug 26, 2014
• Expiry date: Feb 23, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel heterocyclic compounds of the formula (I), in which R1, D, W, T and T′ have the meanings indicated in Claim 1, are SGK inhibitors and can be used for the treatment of SGK-induced diseases and conditions, such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and kidney diseases, generally in fibroses and inflammatory processes of any type.