Prostratin analogs, bryostatin analogs, prodrugs, synthetic methods, and methods of use

US8816122B2 · kind B2 · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Paul A. Wender · Menlo Park, US
• Lars V. Heumann · Redwood City, US
• Rainer Kramer · Freiburg im Breisgau, DE
• Carolyn Gauntlett · Singapore, SG
• Elizabeth Mieuli · Redwood City, US
• Dennis Fournogerakis · Stanford, US
• Pierre-Luc Boudreault · Montréal, CA
• Adam J. Schrier · Redwood City, US
• Brian Addison DECHRISTOPHER · Mountain View, US

Key dates

• Filing date: Jul 20, 2010
• Grant date: Aug 26, 2014
• Expiry date: Apr 5, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/40
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Embodiments of the present disclosure provide for prostratin analogs, bryostatin analogs, prodrugs of prostratin and prostratin analogs, methods of making prostratin analogs, and methods of making prodrugs of prostratin and prostratin analogs, methods of use of prostratin analogs, bryostatin analogs, and prodrugs thereof, and the like.