Stat5b transgenic mice and methods of use thereof
US8816151B2 · kind B2 · utility
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Key dates
| Filing date | Feb 7, 2013 |
| Grant date | Aug 26, 2014 |
| Priority date | — |
| Expiry date | Feb 7, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
It has been discovered that STAT5 phosphorylation and CD150 are effective biomarkers for detecting, diagnosing, and monitoring hematological malignancies, including for example lymphomas. Compositions and methods for identifying therapeutic agents for the treatment of hematologic malignancies using p-STAT5, CD150 or both as biomarkers are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.