Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue
US8821364B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 1, 2009 |
| Grant date | Sep 2, 2014 |
| Priority date | — |
| Expiry date | Dec 3, 2030 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29K2995/006
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A system, method and device for treating tumor cells utilizing a resorbable therapy seed made up of microspheres containing a beta- or alpha-particle-emitting radiation source and a resorbable polymer matrix. These seeds are implanted within the tumor and then rapidly dissolved so as to release the microspheres from the polymer matrix. These microspheres then spread within a preselected target area and provide radiation therapy in a predetermined amount and at a preselected rate according the specific needs and necessities of the users. The configuration of the microspheres, the types of radiation provided and the location and use of these microspheres provides desired localized treatment to target cells while preferentially avoiding or minimizing undesired damage to surrounding tissue. The present invention provides a method for making the seeds, as well as a method for utilizing the seeds as a part of the treatment method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.