Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds and methods of use thereof

US8821871B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Joanne Van Ryn · Warthausen, DE
• Keith Canada · Southbury, US
• Robert Copenhaver · Portland, US
• Norbert Hauel · Schemmerhofen, DE
• Tobias Litzenburger · Mittelbiberach, DE
• Christopher Ronald Sarko · San Ramon, US
• Sanjaya Singh · Sandy Hook, US
• Alisa K. Waterman · Weston, US

Key dates

• Filing date: Mar 28, 2012
• Grant date: Sep 2, 2014
• Expiry date: Mar 28, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.