Pharmaceutical composition comprising antibodies against catalase and superoxide dismutase for tumor therapy
US8821875B2 · kind B2 · utility
2Cited by
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6Claims
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Inventor
Key dates
| Filing date | Jun 15, 2012 |
| Grant date | Sep 2, 2014 |
| Priority date | — |
| Expiry date | Jun 15, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is based on the unexpected finding that, in addition to catalase, SOD is also involved in protecting tumor cells, wherein the inhibition effects of the two protective enzymes support one another in a complementary manner. The invention thus relates to pharmaceutical compositions containing at least two antibodies or the biologically active fragments thereof, wherein the one antibody is directed against the catalase and the other antibody is directed against the superoxide dismutase, as well as their use for treating a tumor disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.