Methods for indexing samples and sequencing multiple polynucleotide templates
US8822150B2 · kind B2 · utility
28Cited by
57References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 11, 2012 |
| Grant date | Sep 2, 2014 |
| Priority date | — |
| Expiry date | Apr 11, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to methods for indexing samples during the sequencing of polynucleotide templates, resulting in the attachment of tags specific to the source of each nucleic acid sample such that after a sequencing run, both the source and sequence of each polynucleotide can be determined. Thus, the present invention pertains to analysis of complex genomes (e.g., human genomes), as well as multiplexing less complex genomes, such as those of bacteria, viruses, mitochondria, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.