Patent · US Active

Bispecific intracellular delivery vehicles

US8822213B2 · kind B2 · utility

13Cited by
20References
23Claims
0Family size

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Key dates

Filing dateMay 13, 2009
Grant dateSep 2, 2014
Priority date
Expiry dateJul 19, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/10
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A composition for delivering an agent to a cell, comprising a bispecific affinity reagent and a pH-responsive, membrane destabilizing polymer. The bispecific affinity reagent may include a first affinity reagent covalently linked to a second affinity reagent, wherein the first affinity reagent binds to a molecule on the surface of a cell, and the second affinity reagent binds to an intracellular target.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.