Tympanic membrane permeating ear drops and uses thereof
US8822410B2 · kind B2 · utility
3Cited by
4References
11Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | May 19, 2009 |
| Grant date | Sep 2, 2014 |
| Priority date | — |
| Expiry date | Feb 16, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P27/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for noninvasive delivery of therapeutic agents across an intact tympanic membrane. For example, the compositions include a penetration enhancer which increases the flux of a therapeutic agent (e.g., antibiotic) across the tympanic membrane. Such compositions are particularly useful in the treatment of otitis media. Additionally, the composition may include a sustained release agents that, in some embodiments form sustained release reservoirs, in situ, once administered to a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.