Bifunctional hormone having alpha-MSH activity and natriuretic peptide activity and uses thereof
US8822413B2 · kind B2 · utility
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25Claims
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Key dates
| Filing date | Jul 7, 2008 |
| Grant date | Sep 2, 2014 |
| Priority date | — |
| Expiry date | Sep 20, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A bifunctional hormone exhibiting an alpha-MSH activity and a natriuretic peptide activity is described. The bifunctional hormone comprises for example a first domain having alpha-MSH related hormonal activity covalently linked to a second domain having natriuretic peptide related hormonal activity. The bifunctional hormone of the present invention is useful for example for the prevention and/or treatment of renal related diseases or conditions, such as acute renal failure (ARF) or acute kidney injury (AKI).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.