Fused cyclopentyl antagonists of CCR2
US8822460B2 · kind B2 · utility
1Cited by
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18Claims
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Assignee
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Key dates
| Filing date | Apr 4, 2013 |
| Grant date | Sep 2, 2014 |
| Priority date | — |
| Expiry date | Apr 4, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention comprises compounds of Formula (I).wherein: R0, R1, R2, R3, R4, R5, and A are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.