Substituted aminopropionic derivatives as neprilysin inhibitors
US8822534B2 · kind B2 · utility
7Cited by
20References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 29, 2012 |
| Grant date | Sep 2, 2014 |
| Priority date | — |
| Expiry date | Nov 29, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a compound of formula I′;or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, B1, X and n are defined herein. The invention also relates a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.