Quaternary heteroatom containing compounds

US8822679B2 · kind B2 · utility

Assignee

• CALIFORNIA INSTITUTE OF TECHNOLOGY · US

Inventors

• Brian M. Stoltz · San Marino, US
• Scott C. Virgil · Pasadena, US
• David E. White · Wayne, US
• Taiga Yurino · Kyoto, JP
• Yiyang Liu · Pasadena, US
• Douglas C. Behenna · San Juan Capistrano, US
• Douglas R. Duquette · Glencoe, US
• Christian Eidamshaus · Mannheim, DE

Key dates

• Filing date: Jun 22, 2012
• Grant date: Sep 2, 2014
• Expiry date: Jul 13, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D309/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A compound useful as a building block for the manufacture of various compounds is represented by Formula A or D.In Formula A and D, z is 0 or 1; Q is a heteroatom; R1 through R11 and Ra through Rf are each independently hydrogen, a substituted or unsubstituted hydrocarbyl group, a substituted or unsubstituted heteroatom containing hydrocarbyl group, or a functional group; d, e and f are each independently 0 or greater; each of A, B and D is independently a carbon atom or a heteroatom; and two or more of R1 though R11, Ra through Rf and Y optionally combine to form a ring. In some embodiments, R8 and R9 combine to form a carbonyl group. In some embodiments, R2 and Y combine to form a ring with the Q atom. In some embodiments, the ring includes at least one double bond.