Patent · US Active

Imidazo[1,2-a]pyridine derivative

US8822688B2 · kind B2 · utility

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0References
12Claims
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Assignee

Inventors

Key dates

Filing dateOct 26, 2012
Grant dateSep 2, 2014
Priority date
Expiry dateNov 3, 2032

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

[Problem]To provide a compound useful as medicine having PDE4B inhibitory activity, in particular, as an active ingredient of a composition for treating or preventing schizophrenia, Alzheimer's disease, dementia, depression and the like.[Measures for Solution]The present inventors examined compounds having PDE4B inhibitory activity and found that a tricyclic or tetracyclic imidazo[1,2-a]pyridine derivative or salts thereof had a superior PDE4B inhibitory activity, thereby completing the present invention. The imidazo[1,2-a]pyridine derivative can be used as an agent for treating or preventing schizophrenia, Alzheimer's disease, dementia, depression and the like.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.