Patent · US Active

Salt forms of [R-(R*,R*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4[phenylamino) carbonyl]-1H-pyrrole-1-heptanoic acid

US8822703B2 · kind B2 · utility

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12References
6Claims
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Key dates

Filing dateSep 3, 2013
Grant dateSep 2, 2014
Priority date
Expiry dateSep 3, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D295/037
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel salt forms of [R—(R*,R*)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid characterized by their X-ray powder diffraction pattern and solid-state NMR spectra are described, as well as methods for the preparation and pharmaceutical composition of the same, which are useful as agents for treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, and Alzheimer's Disease.

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