Patent · US Active

Process for the preparation of hydroxytyrosol

US8822738B1 · kind B1 · utility

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1References

18Claims

0Family size

Assignee

Wacker Chemie AG · DE

Inventors

Benno Krueger · Burghausen, DE
Gerald Fleischmann · Emmerting, DE
Hermann Petersen · Burghausen, DE

Key dates

Filing date	Feb 25, 2014
Grant date	Sep 2, 2014
Priority date	—
Expiry date	Feb 25, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C37/055
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A process for preparing hydroxytyrosol, wherein a compoundwhere X is CH2OH or CH2OM (M=Li, Na, K, Mg, Ca), R1 and R2 are identical or different and are C1-C8 alkyl radical, benzyl radical, alkyl- or halogen-substituted benzyl radical or arylalkyl radical, where R1 and R2 can also be linked viato give a ring, R3, R4, R5 and R6 are identical or different and are hydrogen or C1-C6 alkyl radical, aryl radical, alkyl-substituted aryl radical, where R5 and R6 can also be linked via —(CH2)4—, —(CH2)5— or —(CH2)6— to give a ring, is reacted with an aluminum compound AlR7R8R9 (2), where R7, R8 and R9 are identical or different and are H or C1-C8 alkyl radical, and then an aqueous solution of a hydroxycarboxylic acid is added to form a clear homogeneous acidic solution with a pH<3, and hydroxytyrosol is extracted therefrom.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.