Method of screening a sample for the presence of one or more known compounds of interest and a mass spectrometer performing this method
US8822914B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 6, 2010 |
| Grant date | Sep 2, 2014 |
| Priority date | — |
| Expiry date | May 11, 2031 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/004
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
A method of screening a sample for the presence of one or more known compounds of interest is disclosed. A fragmentation device is repeatedly switched between a fragmentation mode of operation and a non-fragmentation mode of operation. A determination is made whether a candidate parent ion of interest is present in a non-fragmentation data set and whether one or more corresponding fragment ions of interest are present in a fragmentation data set. A further determination is made to check if the candidate parent ion of interest and the one or more corresponding fragment ions of interest have substantially similar elution or retention times and/or ion mobility drift times.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.