Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue
US8825152B2 · kind B2 · utility
18Cited by
393References
62Claims
0Family size
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Key dates
| Filing date | Apr 3, 2002 |
| Grant date | Sep 2, 2014 |
| Priority date | — |
| Expiry date | Apr 3, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/368
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
According to a method and device for modulating intracellular calcium concentration in biological tissue, a stimulation probe is applied to the tissue, a non-excitatory stimulation pulse is generated, and the pulse is conveyed to the stimulation probe. In one embodiment concerning cardiac tissue, a stimulation probe is applied to a patient's heart, a signal is received from at least one sensor responsive to the patient's cardiac muscle activity, a non-excitatory stimulation pulse responsive to the signal is generated, and the pulse is conveyed to the stimulation probe.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.