Device for chromatographic separations
US8828234B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 7, 2010 |
| Grant date | Sep 9, 2014 |
| Priority date | — |
| Expiry date | Jul 9, 2033 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/205
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A device is provided for chromatographic separations comprising a manifold comprising a plurality of connectors for connecting to one or more chromatographic separation columns and/or feed or extraction tubing. At least one central duct is formed between at least two connectors forming an inlet and an outlet respectively. The central duct comprises a closable duct valve; and a plurality of branch ducts branching from the central duct to a branch connector. The branch duct comprises a closable branch valve, wherein at least one branch duct is positioned between the inlet and the central duct valve and wherein at least one branch duct is positioned between the outlet and the central duct valve. The device is arranged for carrying out single-column and (continuous) multicolumn chromatographic separations. This allows the purification of biopharmaceutical products without having to develop, demonstrate and validate cleaning procedures for the valves.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.