Antibody that binds to H-1 parvovirus

US8828400B2 · kind B2 · utility

Assignee

• DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS · DE

Inventors

• Barbara Leuchs · Heidelberg, DE
• Kathrin Kürschner · Heidelberg, DE
• Andrea Kuck · Ittlingen, DE
• Marcus Müller · Bad Rappenau, DE
• Silvia Münstermann · Trochtelfingen, DE
• Jean Rommelaere · Heidelberg, DE

Key dates

• Filing date: Dec 1, 2010
• Grant date: Sep 9, 2014
• Expiry date: Dec 1, 2030

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/015
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Described is an antibody or an antigen binding fragment thereof specifically binding to a full or empty H-1 parvovirus capsid. Such an antibody is useful for various diagnostic and therapeutic methods, e.g., for the detection/therapy of an H-1 parvovirus infection during pregnancy since parvovirus affects about 1 in 400 pregnancies and may cause fetal loss or fetal hydrops.