Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors and HMG-CoA reductase
US8828438B2 · kind B2 · utility
2Cited by
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9Claims
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Key dates
| Filing date | May 22, 2006 |
| Grant date | Sep 9, 2014 |
| Priority date | — |
| Expiry date | Jun 6, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/4706
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A solid amorphous dispersion comprises a cholesteryl ester transfer protein (CETP) inhibitor, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase inhibitor), and a concentration enhancing polymer. At least a major portion of the CETP inhibitor in the dispersion is amorphous. The solid amorphous dispersion provides concentration-enhancement of the CETP inhibitor when administered to an aqueous use environment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.