Fermentive production of four carbon alcohols
US8828704B2 · kind B2 · utility
34Cited by
18References
10Claims
0Family size
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Key dates
| Filing date | Apr 29, 2008 |
| Grant date | Sep 9, 2014 |
| Priority date | — |
| Expiry date | Apr 29, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02E50/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2-butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein. Specifically disclosed herein are the use of coenzyme B12-independent butanediol dehydratases that catalyzes the substrate to product conversion of 2,3-butanediol to 2-butanone in the process of producing 2-butanol and 2-butanone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.