Plectin-1 targeted agents for detection and treatment of pancreatic ductal adenocarcinoma
US8829159B2 · kind B2 · utility
1Cited by
4References
25Claims
0Family size
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Key dates
| Filing date | Apr 14, 2009 |
| Grant date | Sep 9, 2014 |
| Priority date | — |
| Expiry date | Sep 30, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are compositions and methods for cancer cell biomarkers, such as pancreatic ductal adenocarcinoma (PDAC) cell biomarkers, and binding molecules for diagnosis and treatment of cancer, e.g., PDAC. Methods of identifying “accessible” proteomes are disclosed for identifying cancer biomarkers, such as plectin-1, a PDAC biomarker. Additionally, imaging compositions are provided comprising magnetofluorescent nanoparticles conjugated to peptide ligands for identifying PDACs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.